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500 mg pure β-Nicotinamide Mononucleotide per capsule · 90 Capsules · 45-Day Supply
Our highest-potency pure NMN formula designed to support cellular energy, healthy aging, and maximum vitality.
As a dietary supplement, adults take 2 capsules once daily, preferably in the morning on an empty stomach or as directed by a healthcare professional. Take with a full glass of water. For best results, use consistently for a minimum of 8–12 weeks.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have a medical condition. Keep out of reach of children. Store in a cool, dry place.
AIDEVI NMN 45000 is our highest-potency, pure NAD+ booster supplement, delivering a massive 500 mg of pure β-Nicotinamide Mononucleotide (NMN) per capsule. With 90 capsules per bottle, it provides a total of 45,000 mg of NMN across a full 45-day supply. The "45000" in the product name reflects this total NMN content per bottle, a transparent labelling convention that allows consumers to understand exactly what they are getting.
NMN is a direct precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme found in every living cell and essential for energy metabolism, DNA repair, and the activation of longevity-linked proteins called sirtuins. Unlike NAD+ itself — which cannot easily cross cell membranes — NMN is actively transported into cells, where it is rapidly converted into NAD+. This makes NMN supplementation one of the most direct and scientifically validated strategies for restoring cellular NAD+ levels.
AIDEVI NMN 45000 is manufactured in a cGMP-certified facility in the United States and independently verified for purity and potency. By focusing exclusively on pure, high-dose NMN, this formula is designed for individuals seeking maximum NAD+ restoration without additional co-ingredients.
NAD+ is arguably one of the most important molecules in the human body. It serves as the central hub of cellular metabolism, acting as an electron carrier in the mitochondrial energy production chain and as a substrate for critical repair enzymes, including PARPs (Poly ADP-Ribose Polymerases) and sirtuins. Research has established that NAD+ levels decline by approximately 50% between the ages of 40 and 60, a trajectory directly linked to the hallmarks of aging — including mitochondrial dysfunction, genomic instability, and cognitive decline.
Illustrative representation based on peer-reviewed research on age-related NAD+ decline. Individual results may vary.
This decline is not merely a passive consequence of aging — it is an active driver of it. When NAD+ levels fall, mitochondria become less efficient, DNA repair slows, and the sirtuin proteins that regulate cellular stress responses become less active. The result is a cascade of cellular dysfunction that manifests as reduced energy, slower recovery, cognitive fog, and increased susceptibility to age-related conditions.
Multiple human clinical studies have confirmed that oral NMN supplementation safely and significantly increases blood NAD+ levels in healthy adults. A randomised, double-blind study published in the Journal of the International Society of Sports Nutrition demonstrated that NMN doses of 600–1200 mg/day significantly improved aerobic capacity and muscle oxygen utilisation in middle-aged runners, highlighting the profound impact of high-dose NMN on physical performance.
AIDEVI NMN 45000 is designed for one specific purpose: delivering the highest possible dose of pure NMN in a convenient daily serving. By omitting secondary ingredients, this formula allows users to precisely control their NMN intake and maximise NAD+ restoration.
The high-potency NMN in AIDEVI NMN 45000 targets multiple pathways of cellular aging. Here is how the science translates into tangible health benefits:
| Benefit Area | Mechanism of Action | Supporting Evidence |
|---|---|---|
| Physical Endurance & Muscle Function | High-dose NMN (600–1200 mg/day) significantly improves skeletal muscle oxygen utilisation, aerobic capacity (VO2 max), and ventilatory threshold during exercise. | Liao et al., 2021 |
| Cognitive Health & Memory | NMN crosses the blood-brain barrier to elevate brain NAD+ levels, activating SIRT1 to protect hippocampal neurons and support memory retention against age-related decline. | Zhao et al., 2020 |
| Cellular Energy Production | As a direct NAD+ precursor, NMN fuels the mitochondrial electron transport chain, increasing ATP (cellular energy) production and reducing age-related fatigue. | Rahman et al., 2024 |
| DNA Repair & Genomic Stability | NAD+ is the essential substrate for PARP enzymes, which detect and repair DNA damage caused by oxidative stress, UV radiation, and normal metabolic processes. | Nadeeshani et al., 2021 |
| Cardiovascular Health | NMN supports endothelial function and reduces arterial stiffness by enhancing NAD+-dependent energy metabolism in vascular tissues. | Wen et al., 2024 |
AIDEVI NMN 45000 is formulated for adults seeking maximum-strength NAD+ restoration. It is particularly beneficial for:
Clinical trials show that high-dose NMN (up to 1200 mg/day) significantly improves aerobic capacity and muscle oxygen utilisation. Ideal for those looking to boost physical performance and speed up recovery.
For individuals experiencing age-related brain fog or declining focus. NMN supports brain NAD+ levels, which are critical for neuronal health, memory retention, and sustained mental clarity throughout the workday.
For adults over 40 who want to aggressively combat the natural 50% decline in NAD+ levels. The 1000 mg daily dose provides the robust cellular support needed to activate sirtuins and promote long-term vitality.
For biohackers who prefer to build their own supplement stacks. By offering pure NMN without co-ingredients, NMN 45000 allows you to precisely control your NAD+ precursor intake alongside your preferred separate supplements.
As the Nutraceutical Brand of the Year (Corporate LiveWire Global Awards 2025/26), AIDEVI is committed to uncompromising quality, transparency, and safety.
