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AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement
AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement

AIDEVI NAD Plus 15000 | Advanced Cognitive Support & Cellular Vitality Supplement

Nutraceutical Brand of the Year · Corporate LiveWire Global Awards 2025/26

AIDEVI NAD+ 15000 — Direct NAD+ Booster Supplement for Cognitive Health

250 mg Direct NAD+ per capsule · 30 Capsules · 30-Day Supply
A comprehensive multi-pathway formula featuring direct Nicotinamide Adenine Dinucleotide, Nicotinamide, TMG, and Trans-Resveratrol to support brain energy, focus, and cellular vitality.

30-Day Supply
cGMP Certified
Third-Party Tested
Made in USA
BBB Permeable
🧠
Cognitive Clarity
Supports neuroplasticity and helps maintain focus, memory, and mental sharpness
Brain Energy
Fuels mitochondrial energy production in brain cells without the jitters of caffeine
🛡️
Cellular Protection
Combats the causes of brain aging and supports resilience against cognitive decline
🔄
Multi-Pathway Support
Combines direct NAD+ with precursors and TMG for comprehensive cellular restoration
SUPPLEMENT FACTS SNAPSHOT
Serving Size: 1 Capsule  |  Servings Per Container: 30
Ingredient Per Serving (1 Capsule)
Niacin (as Nicotinamide & Nicotinic acid) 140 mg
NAD+ Booster Blend 500 mg
Nicotinamide Adenine Dinucleotide (NAD+) 250 mg
Nicotinamide 100 mg
Trimethylglycine (TMG) 60 mg
trans-Resveratrol 50 mg
Nicotinic acid 40 mg

† Daily Value not established. Other ingredients: Vegetable Cellulose (capsule), Microcrystalline Cellulose, Magnesium Stearate.

📋 Suggested Use

As a dietary supplement, adults take 1 capsule once daily, preferably in the morning to quickly boost your energy to face the day. Mix or replace your morning coffee with NAD+ Supplement to experience the brain-nourishing benefits of this powerful blend.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Avoid use during pregnancy or breastfeeding. Consult your healthcare provider before use if you are taking medication or have a medical condition. Keep out of reach of children. Store in a cool, dry place.

PRODUCT DETAILS

What Is AIDEVI NAD+ 15000?

AIDEVI NAD+ 15000 is our most advanced, all-in-one NAD+ booster supplement specifically formulated to support cognitive health and cellular vitality. Unlike standard supplements that rely solely on precursors, this proprietary formula delivers 250 mg of direct Nicotinamide Adenine Dinucleotide (NAD+) per capsule, alongside a synergistic blend of precursors and co-factors. With 30 capsules per bottle, it provides a total of 15,000 mg of our NAD+ Booster Blend across a full 30-day supply.

NAD+ is a fundamental coenzyme found in every living cell, essential for energy metabolism, DNA repair, and the activation of longevity-linked proteins called sirtuins. The brain is one of the most metabolically demanding organs in the body, consuming roughly 20% of our total energy despite accounting for only 2% of our body weight. This high energy demand makes brain cells particularly vulnerable to the natural decline in NAD+ levels that occurs as we age.

Manufactured in a cGMP-certified facility in the United States, AIDEVI NAD+ 15000 is designed to cross the blood-brain barrier (BBB), ensuring high bioavailability for your brain cells. It provides the comprehensive support needed to counteract the aging process, maintain neuroplasticity, and unlock your brain's hidden abilities.

The Science Behind Brain Aging and NAD+ Decline

After age 30, our cognitive abilities—such as memory, focus, and concentration—begin a subtle but progressive decline. Research indicates that up to 20% of people over 60 will develop mild cognitive impairment (MCI), characterised by a noticeable decline in episodic memory and the ability to recall specific details. A primary driver of this cognitive aging is the systemic depletion of NAD+.

NAD+ Level Decline With Age (Relative to Peak at Age 20)

Age 20 100%
Age 30 ~80%
Age 40 ~60%
Age 50 ~45%
Age 60+ ~30%

Illustrative representation based on peer-reviewed research on age-related NAD+ decline. Individual results may vary.

When NAD+ levels fall, mitochondrial function in neurons becomes impaired, leading to reduced ATP (energy) production. This energy deficit compromises neuroplasticity—the brain's ability to form new neural connections and adapt to new information. Furthermore, depleted NAD+ reduces the activity of DNA repair enzymes (PARPs) and longevity proteins (sirtuins), leaving brain cells vulnerable to oxidative stress and neuroinflammation.

A comprehensive review published in Cell Metabolism (Lautrup et al., 2019) highlights that NAD+ augmentation restores mitochondrial bioenergetics, enhances neuronal survival, and improves cognitive function in models of aging and neurodegeneration. By maintaining youthful NAD+ levels in your body and brain, you can actively counteract the cellular mechanisms that drive cognitive decline.

The AIDEVI NAD+ 15000 Formula: Multi-Pathway Brain Support

Unlike single-ingredient supplements, AIDEVI NAD+ 15000 utilizes a multi-pathway approach to cellular restoration. By combining direct NAD+ with specific precursors and co-factors, this formula ensures that your cells have both the immediate coenzymes and the raw materials needed for sustained energy production.

STAR INGREDIENT Nicotinamide Adenine Dinucleotide (NAD+) — 250 mg

The core of our formula is direct NAD+, the actual coenzyme molecule required by your cells. While precursors like nmn and NR must undergo enzymatic conversion within the body to become NAD+, providing the intact molecule offers an immediate supply for cellular processes. Recent advancements in oral delivery have demonstrated that intact NAD+ can be effectively utilized by the body, particularly when combined with synergistic compounds that protect it during digestion and enhance cellular uptake.

Nicotinamide (100 mg) & Nicotinic Acid (40 mg)

These two forms of Vitamin B3 serve as foundational precursors for NAD+ synthesis via the salvage and Preiss-Handler pathways, respectively. Nicotinamide is rapidly absorbed and converted to NMN, while Nicotinic Acid provides an alternative route to NAD+ production. A 2022 review in Nutrients confirms that supplementation with these precursors effectively raises intracellular NAD+ levels and offers significant neuroprotective benefits against cognitive decline.

Trimethylglycine (TMG) — 60 mg

When NAD+ is consumed by cellular enzymes (like sirtuins), it is broken down into nicotinamide, which must then be methylated to be excreted. This process can deplete the body's methyl pool. TMG acts as a vital methyl donor, supporting the methylation cycle, protecting liver function, and ensuring that high-dose NAD+ supplementation does not lead to methyl depletion.

Trans-Resveratrol — 50 mg

Trans-Resveratrol is a potent polyphenol that acts as a direct activator of SIRT1, the "longevity gene." While NAD+ provides the fuel (co-substrate) for sirtuins, Resveratrol acts as the accelerator pedal. Together, they work synergistically to enhance mitochondrial biogenesis, reduce neuroinflammation, and protect brain cells from oxidative damage.

Evidence-Informed Benefits

The ingredients in AIDEVI NAD+ 15000 are blood-brain barrier (BBB) permeable, ensuring high bioavailability for your brain cells. Here is how the science translates into tangible cognitive benefits:

Benefit Area Mechanism of Action Supporting Evidence
Cognitive Function & Memory NAD+ augmentation restores mitochondrial bioenergetics in neurons, enhancing synaptic plasticity and supporting episodic memory retention against age-related decline. Lautrup et al., 2019
Sustained Brain Energy By fueling the mitochondrial electron transport chain, NAD+ increases ATP production in brain cells, providing clear, focused energy without the jitters associated with stimulants like caffeine. Campbell, 2022
Neuroprotection & DNA Repair NAD+ is the essential substrate for PARP enzymes, which detect and repair DNA damage caused by oxidative stress, protecting neurons from premature apoptosis (cell death). Lautrup et al., 2019
Healthy Aging & Sirtuin Activation The synergistic combination of NAD+ and Trans-Resveratrol strongly activates SIRT1, reducing neuroinflammation and promoting cellular resilience against age-related stressors. Campbell, 2022

Who Is AIDEVI NAD+ 15000 For?

AIDEVI NAD+ 15000 is specifically formulated for adults seeking to protect and enhance their cognitive function. It is particularly beneficial for:

🧠 Professionals Seeking Mental Clarity

For individuals experiencing brain fog, afternoon slumps, or declining focus. This daily cognitive booster helps maintain sharp focus and mental clarity throughout the workday without the crash of espresso.

Adults Over 40

As NAD+ levels naturally decline by up to 50% between ages 40 and 60, proactive supplementation is key. Ideal for those looking to support healthy aging, energy, and hormonal balance.

🛡️ Proactive Brain Health Advocates

For those concerned about age-related cognitive decline and memory loss. By maintaining NAD+ levels in your brain, you provide the support needed to counteract the aging process and maintain neuroplasticity.

🔄 Comprehensive Supplement Users

For those who want an all-in-one solution. Instead of buying separate bottles of NAD+, Nicotinamide, Resveratrol, and TMG, this balanced formula provides a complete, synergistic blend in a single daily capsule.

The AIDEVI Quality Standard

As the Nutraceutical Brand of the Year (Corporate LiveWire Global Awards 2025/26), AIDEVI is committed to uncompromising quality, transparency, and safety.

cGMP Certified
Manufactured in strict compliance with FDA Current Good Manufacturing Practices.
Third-Party Tested
Independent lab verification for purity, potency, and absence of heavy metals.
BBB Permeable
Ingredients selected specifically for their ability to cross the blood-brain barrier.
Made in USA
Proudly formulated, manufactured, and packaged in the United States.

Frequently Asked Questions

What does "NAD+ 15000" mean?
The number 15000 refers to the total milligrams of our proprietary NAD+ Booster Blend contained in one bottle. Each bottle contains 30 capsules, and each capsule provides a potent 500 mg dose of this blend (500 mg × 30 capsules = 15,000 mg total). This transparent naming convention helps you understand exactly how much active ingredient you are purchasing.
How is this different from NMN supplements?
While NMN (Nicotinamide Mononucleotide) is an excellent precursor that the body converts into NAD+, AIDEVI NAD+ 15000 provides direct Nicotinamide Adenine Dinucleotide (250 mg) alongside other precursors like Nicotinamide and Nicotinic Acid. This multi-pathway approach ensures your cells receive both the immediate coenzyme and the building blocks for sustained production. If you prefer a pure NMN approach, consider our AIDEVI NMN 45000.
When is the best time to take NAD+ 15000?
We recommend taking your daily capsule in the morning. Because NAD+ fuels cellular energy production, taking it early in the day helps optimize your brain's potential, providing sustained focus and mental clarity without interfering with your sleep cycle at night. Many users successfully mix or replace their morning coffee with this supplement.
How long does it take to see results?
Many users report feeling a subtle increase in mental clarity and sustained energy within the first few days to a week of use. However, for long-term neuroprotective benefits and cellular repair, consistent daily use over several months is recommended, as the formula works to counteract the cumulative effects of brain aging.
Why is TMG included in the formula?
When your cells utilize NAD+, it is broken down into nicotinamide, which must be methylated to be excreted. This process can deplete your body's methyl reserves. TMG (Trimethylglycine) is included as a vital methyl donor to support healthy methylation pathways, ensuring that boosting your NAD+ levels doesn't cause imbalances elsewhere in your metabolism. Learn more about TMG here.
Is this supplement safe for daily use?
Yes, the ingredients in AIDEVI NAD+ 15000 are generally recognized as safe for daily consumption by healthy adults. However, as with any dietary supplement, you should consult your healthcare provider before starting, especially if you are pregnant, nursing, taking medication, or have a pre-existing medical condition.

Scientific References

  1. Lautrup, S., Sinclair, D. A., Mattson, M. P., & Fang, E. F. (2019). NAD+ in Brain Aging and Neurodegenerative Disorders. Cell Metabolism, 30(4), 630–655. https://pmc.ncbi.nlm.nih.gov/articles/PMC6787556/
  2. Campbell, J. M. (2022). Supplementation with NAD+ and Its Precursors to Prevent Cognitive Decline across Disease Contexts. Nutrients, 14(15), 3231. https://pmc.ncbi.nlm.nih.gov/articles/PMC9370773/
  3. Yi, L., Maier, A. B., Tao, R., Lin, Z., Vaidya, A., Pendse, S., Thasma, S., Andhalkar, N., Avhad, G., & Kumbhar, V. (2023). The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial. GeroScience, 45(1), 29–43. https://pmc.ncbi.nlm.nih.gov/articles/PMC9735188/
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