NMN Can Promote Physiological and Metabolic Functions in the Elderly

With the advancement of science and technology, human pursuit of health and longevity is increasingly growing. In recent years, NMN has garnered widespread attention as an emerging nutritional supplement. So, can the elderly take NMN? What are its promoting effects on the physiological functions and metabolism of the elderly?

NMN is a naturally occurring substance that can be converted into NAD+ in the human body, which is a coenzyme critical in cellular metabolism. As age increases, the level of NAD+ in the body gradually decreases, leading to a series of age-related physiological and metabolic issues. Therefore, supplementing NMN to elevate NAD+ levels can slow down the aging process and improve the physiological functions and metabolic status of the elderly.

Promoting Effects of NMN on the Physiological Functions of the Elderly

1. Improving Mitochondrial Function:

Experimental Procedure: In 2013, a research team at the University of Washington published a paper in the journal "Cell Metabolism." They selected two groups of elderly mice, one receiving NMN treatment and the other as a control. During the experiment, scientists monitored the quantity, activity, and energy generation efficiency of mitochondria in mice. They evaluated changes in mitochondrial function through tissue slicing and biochemical analysis.

Conclusion: After a period of time, they found that the mice supplemented with NMN showed increased mitochondrial quantity, improved activity, and significantly enhanced energy generation efficiency. This indicates that NMN can improve mitochondrial function, thereby enhancing the physical strength and endurance of the elderly.

2. Boosting Immunity:

Experimental Procedure: In 2018, a research team at Kyoto University published a paper in the journal "Nature." They injected NMN into elderly mice and monitored the activity of their immune cells. Through flow cytometry and immunohistochemistry techniques, they analyzed the expression of longevity proteins in immune cells.

Conclusion: The experimental results showed that after NMN injection, the activity of immune cells in mice increased, and the expression level of longevity proteins increased. This suggests that NMN may enhance the immunity of the elderly by activating longevity proteins in immune cells.

3. Promoting Neurological Health:

Experimental Procedure: A research team at Harvard University fed elderly mice with NMN-containing food and conducted tests on cognitive function and memory. They used maze and other testing tools to evaluate the performance of mice.

Conclusion: After a period of feeding, the NMN group of mice showed significantly better performance in cognitive function and memory compared to the control group. This indicates that NMN may play a positive role in preventing cognitive impairment in the elderly.

Promoting Effects of NMN on the Metabolism of the Elderly

a. Improving Insulin Resistance:

Experimental Procedure: In 2016, a research team at the University of California published a paper in the journal "Diabetologia." They fed elderly mice with NMN-containing food and monitored their insulin sensitivity.

Conclusion: The experimental results showed that after NMN injection, the insulin sensitivity of mice significantly improved. This suggests that NMN may help improve the glucose metabolism of the elderly and reduce the risk of diabetes.

b. Promoting Fat Metabolism:

Experimental Procedure: In 2018, a research team at the Massachusetts Institute of Technology published a study in the journal "Cell Metabolism." They exposed fat cells to NMN-containing culture medium, observed the metabolism of fat cells, and measured the oxidation of fatty acids and the synthesis of lipids.

Conclusion: The experimental results showed that NMN could promote the normal metabolism of fat cells, increase the oxidation of fatty acids, and reduce the synthesis of lipids. This helps to reduce obesity problems in the elderly.

c. Protecting Cardiovascular Health:

Experimental Procedure: In 2019, a research team at Stanford University published a study in the journal "Circulation Research." They fed mice with NMN-containing food and used ultrasound technology to evaluate the function of the heart and blood vessels, and detected oxidative stress markers.

Conclusion: The experimental results showed that the cardiovascular function of mice in the NMN group improved, and oxidative stress response decreased. This indicates that NMN may help protect the cardiovascular health of the elderly.

Therefore, we can conclude that NMN can have positive effects on the physiological functions and metabolism of the elderly. However, despite the supporting evidence from the above experiments, research on its safety and efficacy in the elderly population is still limited. Therefore, before deciding whether to supplement NMN, it is advisable for the elderly to consult a doctor or professional nutritionist.